|
Symbol Name ID |
Cav1
caveolin 1, caveolae protein MGI:102709 |
| Darker colors indicate more annotations |
| Human Phenotypes | Right ventricular dilatation |
Right ventricular hypertrophy |
Pulmonary arterial medial hypertrophy |
Pulmonary aterial intimal fibrosis |
Arterial intimal fibrosis |
Abnormal cardiovascular system physiology |
Elevated right atrial pressure |
Right ventricular failure |
Abnormally loud pulmonic component of the second heart sound |
Heart murmur |
Tricuspid regurgitation |
Hypertension |
Elevated pulmonary artery pressure |
Pulmonary arterial hypertension |
Pulmonary arterial hypertension with lack of acute response to NO challenge |
Increased pulmonary vascular resistance |
Elevated jugular venous pressure |
Palpitations |
Atrial flutter |
First degree atrioventricular block |
Right bundle branch block |
Angina pectoris |
Syncope |
Splenomegaly |
Hepatosplenomegaly |
Pulmonary artery vasoconstriction |
Telangiectasia |
| Disease(s) Associated with CAV1 | |||||||||||||||||||||||||||
| congenital generalized lipodystrophy type 3 | |||||||||||||||||||||||||||
| primary pulmonary hypertension | |||||||||||||||||||||||||||
| systemic scleroderma |
| Mouse Phenotypes | abnormal pulmonary endothelial cell surface |
abnormal vascular endothelial cell morphology |
abnormal brain vasculature morphology |
abnormal lung vasculature morphology |
abnormal myocardium layer morphology |
myocardial fiber disarray |
heart left ventricle hypertrophy |
heart right ventricle hypertrophy |
thick interventricular septum |
thin interventricular septum |
cardiac hypertrophy |
increased heart left ventricle weight |
decreased heart left ventricle posterior wall thickness |
increased heart left ventricle wall thickness |
dilated heart left ventricle |
dilated heart right ventricle |
cardiac fibrosis |
dilated cardiomyopathy |
pulmonary hyperemia |
decreased cardiac muscle contractility |
decreased ventricle muscle contractility |
increased heart rate |
pulmonary hypertension |
increased systemic arterial blood pressure |
increased vascular permeability |
abnormal vasoconstriction |
decreased vasoconstriction |
abnormal vasodilation |
increased vasodilation |
abnormal vascular wound healing |
congestive heart failure |
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| Availability | Mouse Genotype | |||||||||||||||||||||||||||||||
| Cav1em2(IMPC)Ics/Cav1em2(IMPC)Ics | ||||||||||||||||||||||||||||||||
| Cav1tm1Krc/Cav1tm1Krc | ||||||||||||||||||||||||||||||||
| Cav1tm1Kur/Cav1tm1Kur | ||||||||||||||||||||||||||||||||
| Cav1tm1Mls/Cav1tm1Mls | ||||||||||||||||||||||||||||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/23/2024 MGI 6.23 |
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